Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5

Elastic fiber assembly requires deposition of elastin monomers onto microfibrils, the mechanism of which is incompletely understood. Here we show that latent TGF-β binding protein 4 (LTBP-4) potentiates formation of elastic fibers through interacting with fibulin-5, a tropoelastin-binding protein ne...

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Main Authors: Noda, Kazuo, Dabovic, Branka, Takagi, Kyoko, Inoue, Tadashi, Horiguchi, Masahito, Hirai, Maretoshi, Fujikawa, Yusuke, Akama, Tomoya O., Kusumoto, Kenji, Zilberberg, Lior, Sakai, Lynn Y., Koli, Katri, Naitoh, Motoko, von Melchner, Harald, Suzuki, Shigehiko, Rifkin, Daniel B., Nakamura, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581912/
https://ncbi.nlm.nih.gov/pubmed/23382201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215779110
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