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Function of Latent TGFβ Binding Protein 4 and Fibulin 5 in Elastogenesis and Lung Development
Mice deficient in Latent TGFβ Binding Protein 4 (Ltbp4) display a defect in lung septation and elastogenesis. The lung septation defect is normalized by genetically decreasing TGFβ2 levels. However, the elastic fiber assembly is not improved in Tgfb2(−/−);Ltbp4S(−/−) compared to Ltbp4S(−/−) lungs. W...
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| Publicado en: | J Cell Physiol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4436707/ https://ncbi.nlm.nih.gov/pubmed/24962333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24704 |
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