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Dual Functions for LTBP in Lung Development: LTBP-4 Independently Modulates Elastogenesis and TGF-β Activity
The latent TGF-β binding proteins (LTBP) −1, −3, and −4 are extracellular proteins that assist in the secretion and localization of latent TGF-β. The null mutation of LTBP-4S in mice causes defects in the differentiation of terminal air-sacs, fragmented elastin, and colon carcinomas. We investigated...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719250/ https://ncbi.nlm.nih.gov/pubmed/19016471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21643 |
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