Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice

LTBP-4L and LTBP-4S are two isoforms of the extracellular matrix protein latent-transforming growth factor beta-binding protein 4 (LTBP-4). The mutational inactivation of both isoforms causes autosomal recessive cutis laxa type 1C (ARCL1C) in humans and an ARCL1C-like phenotype in Ltbp4(−/−) mice, b...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Bultmann-Mellin, Insa, Essers, Jeroen, van Heijingen, Paula M., von Melchner, Harald, Sengle, Gerhard, Sterner-Kock, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117228/
https://ncbi.nlm.nih.gov/pubmed/27585882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.026005
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