Disruption of the gene encoding the latent transforming growth factor-β binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

Transforming growth factor-βs (TGF-βs) are multifunctional growth factors that are secreted as inactive (latent) precursors in large protein complexes. These complexes include the latency-associated propeptide (LAP) and a latent transforming growth factor-β binding protein (LTBP). Four isoforms of L...

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Pubblicato in:	Genes Dev
Autori principali:	Sterner-Kock, Anja, Thorey, Irmgard S., Koli, Katri, Wempe, Frank, Otte, Jürgen, Bangsow, Thorsten, Kuhlmeier, Katharina, Kirchner, Thomas, Jin, Shenchu, Keski-Oja, Jorma, von Melchner, Harald
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2002
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12208849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.229102
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