Disruption of the gene encoding the latent transforming growth factor-β binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

Transforming growth factor-βs (TGF-βs) are multifunctional growth factors that are secreted as inactive (latent) precursors in large protein complexes. These complexes include the latency-associated propeptide (LAP) and a latent transforming growth factor-β binding protein (LTBP). Four isoforms of L...

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Detalhes bibliográficos
Main Authors: Sterner-Kock, Anja, Thorey, Irmgard S., Koli, Katri, Wempe, Frank, Otte, Jürgen, Bangsow, Thorsten, Kuhlmeier, Katharina, Kirchner, Thomas, Jin, Shenchu, Keski-Oja, Jorma, von Melchner, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC186672/
https://ncbi.nlm.nih.gov/pubmed/12208849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.229102
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