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Function of Latent TGFβ Binding Protein 4 and Fibulin 5 in Elastogenesis and Lung Development

Mice deficient in Latent TGFβ Binding Protein 4 (Ltbp4) display a defect in lung septation and elastogenesis. The lung septation defect is normalized by genetically decreasing TGFβ2 levels. However, the elastic fiber assembly is not improved in Tgfb2(−/−);Ltbp4S(−/−) compared to Ltbp4S(−/−) lungs. W...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Physiol
Egile Nagusiak: Dabovic, Branka, Robertson, Ian B., Zilberberg, Lior, Vassallo, Melinda, Davis, Elaine C., Rifkin, Daniel B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436707/
https://ncbi.nlm.nih.gov/pubmed/24962333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24704
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