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Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension
Amphetamine (AMPH) or methamphetamine (METH) abuse can cause oxidative damage and is a risk factor for diseases including pulmonary arterial hypertension (PAH). Pulmonary artery endothelial cells (PAECs) from AMPH-associated-PAH patients show DNA damage as judged by γH2AX foci and DNA comet tails. W...
Shranjeno v:
| izdano v: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5256132/ https://ncbi.nlm.nih.gov/pubmed/28138562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90427 |
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