RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension is characterized by endothelial dysregulation, but global changes in gene expression have not been related to perturbations in function. Objectives: RNA sequencing was used to discriminate changes in transcriptomes of endothelial cells cultured from lungs o...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Rhodes, Christopher J., Im, Hogune, Cao, Aiqin, Hennigs, Jan K., Wang, Lingli, Sa, Silin, Chen, Pin-I, Nickel, Nils P., Miyagawa, Kazuya, Hopper, Rachel K., Tojais, Nancy F., Li, Caiyun G., Gu, Mingxia, Spiekerkoetter, Edda, Xian, Zhaoying, Chen, Rui, Zhao, Mingming, Kaschwich, Mark, del Rosario, Patricia A., Bernstein, Daniel, Zamanian, Roham T., Wu, Joseph C., Snyder, Michael P., Rabinovitch, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584250/
https://ncbi.nlm.nih.gov/pubmed/26030479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201408-1528OC
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