Consequences of BMPR2 Deficiency in the Pulmonary Vasculature and Beyond: Contributions to Pulmonary Arterial Hypertension

Por Andruska, Adam, Spiekerkoetter, Edda
Publicado no Int J Mol Sci (2018)

Targeting BMPR2 Trafficking with Chaperones: An Important Step toward Precision Medicine in Pulmonary Arterial Hypertension

Por Andruska, Adam, Ali, Mohammed Khadem, Spiekerkoetter, Edda
Publicado no Am J Respir Cell Mol Biol (2020)

Novel Advances in Modifying BMPR2 Signaling in PAH

Por Dannewitz Prosseda, Svenja, Ali, Md Khadem, Spiekerkoetter, Edda
Publicado no Genes (Basel) (2020)

Drug repositioning in pulmonary arterial hypertension: challenges and opportunities

Por Grinnan, Daniel, Trankle, Cory, Andruska, Adam, Bloom, Bruce, Spiekerkoetter, Edda
Publicado no Pulm Circ (2019)

New and Emerging Therapies for Pulmonary Arterial Hypertension

Por Spiekerkoetter, Edda, Kawut, Steven M., de Jesus Perez, Vinicio A.
Publicado no Annu Rev Med (2018)

Targeting the Wnt signaling pathways in pulmonary arterial hypertension

Por de Jesus Perez, Vinicio, Yuan, Ke, Alastalo, Tero-Pekka, Spiekerkoetter, Edda, Rabinovitch, Marlene
Publicado no Drug Discov Today (2014)

Repurposing of medications for pulmonary arterial hypertension

Por Toshner, Mark, Spiekerkoetter, Edda, Bogaard, Harm, Hansmann, Georg, Nikkho, Sylvia, Prins, Kurt W.
Publicado no Pulm Circ (2020)

Current Clinical Management of Pulmonary Arterial Hypertension

Por Zamanian, Roham T, Kudelko, Kristina T, Sung, Yon K, Perez, Vinicio de Jesus, Liu, Juliana, Spiekerkoetter, Edda
Publicado no Circ Res (2014)

Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors

Por Shin, Kunyoo, Lim, Agnes, Zhao, Chen, Sahoo, Debashis, Pan, Ying, Spiekerkoetter, Edda, Liao, Joseph C., Beachy, Philip A.
Publicado no Cancer Cell (2014)

Exome data clouds the pathogenicity of genetic variants in Pulmonary Arterial Hypertension

Por Abbasi, Yeganeh, Jabbari, Javad, Jabbari, Reza, Glinge, Charlotte, Izadyar, Seyed Bahador, Spiekerkoetter, Edda, Zamanian, Roham T., Carlsen, Jørn, Tfelt‐Hansen, Jacob
Publicado no Mol Genet Genomic Med (2018)

A case of recurrent pericardial constriction presenting with severe pulmonary hypertension

Por Brunner, Nathan W., Ramachandran, Krithika, Kudelko, Kristina T., Sung, Yon K., Spiekerkoetter, Edda, Yang, Phillip C., Zamanian, Roham T., Perez, Vinicio de Jesus
Publicado em 2013

The left ventricle undergoes biomechanical and gene expression changes in response to increased right ventricular pressure overload

Por Kheyfets, Vitaly O., Dufva, Melanie J., Boehm, Mario, Tian, Xuefeit, Qin, Xulei, Tabakh, Jennifer E., Truong, Uyen, Ivy, Dunbar, Spiekerkoetter, Edda
Publicado no Physiol Rep (2020)

Myocardial bridge: an unrecognized cause of chest pain in pulmonary arterial hypertension

Por Rajmohan, Divya, Sung, Yon K., Kudelko, Kristina, Perez, Vinicio de Jesus, Haddad, Francois, Tremmel, Jennifer A., Schnittger, Ingela, Zamanian, Roham T., Spiekerkoetter, Edda
Publicado no Pulm Circ (2020)

Neutrophil Elastase Is Produced by Pulmonary Artery Smooth Muscle Cells and Is Linked to Neointimal Lesions

Por Kim, Yu-Mee, Haghighat, Leila, Spiekerkoetter, Edda, Sawada, Hirofumi, Alvira, Cristina M., Wang, Lingli, Acharya, Swati, Rodriguez-Colon, Gabriela, Orton, Andrew, Zhao, Mingming, Rabinovitch, Marlene
Publicado em 2011

A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017

Por Kuebler, Wolfgang M., Nicolls, Mark R., Olschewski, Andrea, Abe, Kohtaro, Rabinovitch, Marlene, Stewart, Duncan, Chan, Stephen Y., Morrell, Nicholas W., Archer, Stephen L., Spiekerkoetter, Edda
Publicado no Am J Physiol Lung Cell Mol Physiol (2018)

Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure

Por Spiekerkoetter, Edda, Goncharova, Elena A., Guignabert, Christophe, Stenmark, Kurt, Kwapiszewska, Grazyna, Rabinovitch, Marlene, Voelkel, Norbert, Bogaard, Harm J., Graham, Brian, Pullamsetti, Soni S., Kuebler, Wolfgang M.
Publicado no Pulm Circ (2019)

Career Development of Young Physician Scientists in the Cardiovascular Sciences: Perspective and Advice from the Early Career Committee of the Cardiopulmonary, Critical Care and Re...

Por Agarwal, Sachin, Spiekerkoetter, Edda, Austin, Eric, de Jesus Perez, Vinicio, Dezfulian, Cameron, Maron, Bradley, Ryan, John J., Starks, Monique A., Yu, Paul, Bonnet, Sebastien, Perman, Sarah M.
Publicado no Circ Res (2018)

Comparative analysis on the anti-inflammatory/immune effect of mesenchymal stem cell therapy for the treatment of pulmonary arterial hypertension

Por Oh, Seyeon, Jang, Albert Y., Chae, Sehyun, Choi, Seungbum, Moon, Jeongsik, Kim, Minsu, Spiekerkoetter, Edda, Zamanian, Roham T., Yang, Phillip C., Hwang, Daehee, Byun, Kyunghee, Chung, Wook-Jin
Publicado no Sci Rep (2021)

Update in Pulmonary Vascular Disease 2016 and 2017

Por Brittain, Evan L., Thennapan, Thennapan, Maron, Bradley A., Chan, Stephen Y., Austin, Eric D., Spiekerkoetter, Edda, Bogaard, Harm J., Guignabert, Christophe, Paulin, Roxane, Machado, Roberto F., Yu, Paul B.
Publicado no Am J Respir Crit Care Med (2018)

S100A4 and BMP-2 Co-Dependently Induce Vascular Smooth Muscle Cell Migration via pERK and Chloride Intracellular Channel 4 (CLIC4)

Por Spiekerkoetter, Edda, Guignabert, Christophe, de Jesus Perez, Vinicio, Alastalo, Tero-Pekka, Powers, Janine M, Wang, Lingli, Lawrie, Allan, Ambartsumian, Noona, Schmidt, Ann-Marie, Berryman, Mark, Ashley, Richard H, Rabinovitch, Marlene
Publicado em 2009