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Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors

Hedgehog (Hh) pathway inhibitors are clinically effective in treatment of basal cell carcinoma and medulloblastoma, but fail therapeutically or even accelerate progression in treatment of endodermally-derived colon and pancreatic cancers. In bladder, another organ of endodermal origin, we find that...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Cell
Päätekijät: Shin, Kunyoo, Lim, Agnes, Zhao, Chen, Sahoo, Debashis, Pan, Ying, Spiekerkoetter, Edda, Liao, Joseph C., Beachy, Philip A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326077/
https://ncbi.nlm.nih.gov/pubmed/25314078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2014.09.001
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