Control of inflammation by stromal Hedgehog pathway activation restrains colitis

Inflammation disrupts tissue architecture and function, thereby contributing to the pathogenesis of diverse diseases; the signals that promote or restrict tissue inflammation thus represent potential targets for therapeutic intervention. Here, we report that genetic or pharmacologic Hedgehog pathway...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lee, John J., Rothenberg, Michael E., Seeley, E. Scott, Zimdahl, Bryan, Kawano, Sally, Lu, Wan-Jin, Shin, Kunyoo, Sakata-Kato, Tomoyo, Chen, James K., Diehn, Maximilian, Clarke, Michael F., Beachy, Philip A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127312/
https://ncbi.nlm.nih.gov/pubmed/27815529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616447113
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