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Spatially restricted Hedgehog signaling regulates HGF-induced branching of the adult prostate

Branching morphogenesis is thought to be governed by epithelial-stromal interactions, but the mechanisms underlying specification of branch location remain largely unknown. Prompted by the striking absence of Hedgehog (Hh) response at the sites of nascent buds in regenerating tubules of the adult pr...

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Bibliografske podrobnosti
izdano v:Nat Cell Biol
Main Authors: Lim, Agnes, Shin, Kunyoo, Zhao, Chen, Kawano, Sally, Beachy, Philip A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327780/
https://ncbi.nlm.nih.gov/pubmed/25362352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3057
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