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Spatially restricted Hedgehog signaling regulates HGF-induced branching of the adult prostate

Branching morphogenesis is thought to be governed by epithelial-stromal interactions, but the mechanisms underlying specification of branch location remain largely unknown. Prompted by the striking absence of Hedgehog (Hh) response at the sites of nascent buds in regenerating tubules of the adult pr...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Lim, Agnes, Shin, Kunyoo, Zhao, Chen, Kawano, Sally, Beachy, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327780/
https://ncbi.nlm.nih.gov/pubmed/25362352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3057
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