Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1 Mediated Metabolic and Epigenetic Changes

RATIONALE: Maintaining endothelial cells (EC) as a monolayer in the vessel wall depends on their metabolic state and gene expression profile, features influenced by contact with neighboring cells such as pericytes and smooth muscle cells (SMC). Failure to regenerate a normal EC monolayer in response...

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Publicado en:Circ Res
Autores principales: Miyagawa, Kazuya, Shi, Minyi, Chen, Pin-I, Hennigs, Jan K, Zhao, Zhixin, Wang, Mouer, Li, Caiyun G, Saito, Toshie, Taylor, Shalina, Sa, Silin, Cao, Aiqin, Wang, Lingli, Snyder, Michael P, Rabinovitch, Marlene
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400637/
https://ncbi.nlm.nih.gov/pubmed/30582451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313374
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