Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1 Mediated Metabolic and Epigenetic Changes

RATIONALE: Maintaining endothelial cells (EC) as a monolayer in the vessel wall depends on their metabolic state and gene expression profile, features influenced by contact with neighboring cells such as pericytes and smooth muscle cells (SMC). Failure to regenerate a normal EC monolayer in response...

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Vydáno v:Circ Res
Hlavní autoři: Miyagawa, Kazuya, Shi, Minyi, Chen, Pin-I, Hennigs, Jan K, Zhao, Zhixin, Wang, Mouer, Li, Caiyun G, Saito, Toshie, Taylor, Shalina, Sa, Silin, Cao, Aiqin, Wang, Lingli, Snyder, Michael P, Rabinovitch, Marlene
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400637/
https://ncbi.nlm.nih.gov/pubmed/30582451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313374
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