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Activation of integrin α5 mediated by flow requires its translocation to membrane lipid rafts in vascular endothelial cells
Local flow patterns determine the uneven distribution of atherosclerotic lesions. Membrane lipid rafts and integrins are crucial for shear stress-regulated endothelial function. In this study, we investigate the role of lipid rafts and integrin α5 in regulating the inflammatory response in endotheli...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725528/ https://ncbi.nlm.nih.gov/pubmed/26733684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524523113 |
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