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Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts
Whether or how the activation of Lck and Fyn during T cell receptor (TCR) signaling is coordinated, and their delivery of function integrated, is unknown. Here we show that lipid rafts function to segregate Lck and Fyn in T cells before activation. Coaggregation of TCR and CD4 leads to Lck activatio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193969/ https://ncbi.nlm.nih.gov/pubmed/12732664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022112 |
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