Lys66 residue as a determinant of high mismatch extension and misinsertion rates of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT)

Por Lwatula, Chisanga, Garforth, Scott J., Prasad, Vinayaka R.
Publicado em 2012

The Lysine 65 Residue in HIV-1 Reverse Transcriptase Function and in Nucleoside Analog Drug Resistance

Por Garforth, Scott J., Lwatula, Chisanga, Prasad, Vinayaka R.
Publicado em 2014

Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase

Por Garforth, Scott J., Wu, Yan Yun, Prasad, Vinayaka R.
Publicado em 2006

Utilization of a Deoxynucleoside Diphosphate Substrate by HIV Reverse Transcriptase

Por Garforth, Scott J., Parniak, Michael A., Prasad, Vinayaka R.
Publicado em 2008

Unusually wide co-factor tolerance in a metalloenzyme; divalent metal ions modulate endo–exonuclease activity in T5 exonuclease

Por Garforth, Scott J., Patel, Dipak, Feng, Min, Sayers, Jon R.
Publicado em 2001

Mutagenesis of conserved lysine residues in bacteriophage T5 5′-3′ exonuclease suggests separate mechanisms of endoand exonucleolytic cleavage

Por Garforth, Scott J., Ceska, Thomas A., Suck, Dietrich, Sayers, Jon R.
Publicado em 1999

An Anaerobic-Type α-Ketoglutarate Ferredoxin Oxidoreductase Completes the Oxidative Tricarboxylic Acid Cycle of Mycobacterium tuberculosis

Por Baughn, Anthony D., Garforth, Scott J., Vilchèze, Catherine, Jacobs, William R.
Publicado em 2009

Probing the Active Site Steric Flexibility of HIV-1 Reverse Transcriptase: Different Constraints for DNA- versus RNA-Templated Synthesis()

Por Silverman, Adam P., Garforth, Scott J., Prasad, Vinayaka R., Kool, Eric T.
Publicado em 2008

The Two-Component Regulatory System senX3-regX3 Regulates Phosphate-Dependent Gene Expression in Mycobacterium smegmatis

Por Glover, Robert T., Kriakov, Jordan, Garforth, Scott J., Baughn, Anthony D., Jacobs, William R.
Publicado em 2007

SITE-DIRECTED MUTAGENESIS IN THE FINGERS SUBDOMAIN OF HIV-1 REVERSE TRANSCRIPTASE REVEALS A SPECIFIC ROLE FOR THE β3-β4 HAIRPIN LOOP IN dNTP...

Por Garforth, Scott J., Kim, Tae Woo, Parniak, Michael A., Kool, Eric T., Prasad, Vinayaka R.
Publicado em 2006

A Herpes Simplex Virus (HSV)-2 Single-Cycle Candidate Vaccine Deleted in Glycoprotein D Protects Male Mice From Lethal Skin Challenge With Clinical Isolates of HSV-1 and HSV-2

Por Burn, Clare, Ramsey, Natalie, Garforth, Scott J, Almo, Steven, Jacobs, William R, Herold, Betsy C
Publicado no J Infect Dis (2018)

Protein production from the structural genomics perspective: achievements and future needs

Por Almo, Steven C, Garforth, Scott J, Hillerich, Brandan S, Love, James D, Seidel, Ronald D, Burley, Stephen K
Publicado em 2013

K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies

Por Garforth, Scott J., Domaoal, Robert A., Lwatula, Chisanga, Landau, Mark J., Meyer, Amanda J., Anderson, Karen S., Prasad, Vinayaka R.
Publicado em 2010

Pre-steady state kinetic analysis of cyclobutyl derivatives of 2’-deoxyadenosine 5’-triphosphate as inhibitors of HIV-1 reverse transcriptase

Por Kim, Jiae, Wang, Ligong, Li, Yongfeng, Becnel, Kimberlynne D., Frey, Kathleen M., Garforth, Scott J., Prasad, Vinayaka R., Schinazi, Raymond F., Liotta, Dennis C., Anderson, Karen S.
Publicado em 2012

Receptor Tyrosine Kinases, TYRO3, AXL, and MER, Demonstrate Distinct Patterns and Complex Regulation of Ligand-induced Activation

Por Tsou, Wen-I, Nguyen, Khanh-Quynh N., Calarese, Daniel A., Garforth, Scott J., Antes, Anita L., Smirnov, Sergey V., Almo, Steve C., Birge, Raymond B., Kotenko, Sergei V.
Publicado em 2014

Identification of Mycobacterial Ribosomal Proteins as Targets for CD4(+) T Cells That Enhance Protective Immunity in Tuberculosis

Por Kennedy, Steven C., Johnson, Alison J., Bharrhan, Sushma, Lindestam Arlehamn, Cecilia S., Xu, Jiayong, Garforth, Scott J., Chan, John, Jacobs, William R., Sette, Alessandro, Almo, Steven C., Porcelli, Steven A.
Publicado no Infect Immun (2018)

Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity

Por Nguyen, Khanh-Quynh N., Tsou, Wen-I, Calarese, Daniel A., Kimani, Stanley G., Singh, Sukhwinder, Hsieh, Shelly, Liu, Yongzhang, Lu, Bin, Wu, Yi, Garforth, Scott J., Almo, Steve C., Kotenko, Sergei V., Birge, Raymond B.
Publicado em 2014

A naturally occurring antiviral ribonucleotide encoded by the human genome

Por Gizzi, Anthony S., Grove, Tyler L., Arnold, Jamie J., Jose, Joyce, Jangra, Rohit K, Garforth, Scott J., Du, Quan, Cahill, Sean M., Dulyaninova, Natalya G., Love, James D., Chandran, Kartik, Bresnick, Anne R., Cameron, Craig E., Almo, Steven C.
Publicado no Nature (2018)

Panoramic view of a superfamily of phosphatases through substrate profiling

Por Huang, Hua, Pandya, Chetanya, Liu, Chunliang, Al-Obaidi, Nawar F., Wang, Min, Zheng, Li, Toews Keating, Sarah, Aono, Miyuki, Love, James D., Evans, Brandon, Seidel, Ronald D., Hillerich, Brandan S., Garforth, Scott J., Almo, Steven C., Mariano, Patrick S., Dunaway-Mariano, Debra, Allen, Karen N., Farelli, Jeremiah D.
Publicado no Proc Natl Acad Sci U S A (2015)