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Protein production from the structural genomics perspective: achievements and future needs

Despite a multitude of recent technical breakthroughs speeding high-resolution structural analysis of biological macromolecules, production of sufficient quantities of well-behaved, active protein continues to represent the rate-limiting step in many structure determination efforts. These challenges...

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Detalhes bibliográficos
Main Authors: Almo, Steven C, Garforth, Scott J, Hillerich, Brandan S, Love, James D, Seidel, Ronald D, Burley, Stephen K
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163025/
https://ncbi.nlm.nih.gov/pubmed/23642905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2013.02.014
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