Structural and Mechanistic Characterization of L-Histidinol Phosphate Phosphatase from the PHP Family of Proteins

l-Histidinol phosphate phosphatase (HPP) catalyzes the hydrolysis of L-histidinol phosphate to L-histidinol and inorganic phosphate, the penultimate step in the biosynthesis of L-histidine. HPP from the polymerase and histidinol phosphatase (PHP) family of proteins possesses a trinuclear active site...

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Detalhes bibliográficos
Main Authors: Ghodge, Swapnil V., Fedorov, Alexander A., Fedorov, Elena V., Hillerich, Brandan, Seidel, Ronald, Almo, Steven C., Raushel, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570733/
https://ncbi.nlm.nih.gov/pubmed/23327428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301496p
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