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Identification and structural characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis

The absence of a histidine biosynthesis pathway in humans, coupled with histidine essentiality for survival of the important human pathogen Mycobacterium tuberculosis (Mtb), underscores the importance of the bacterial enzymes of this pathway as major antituberculosis drug targets. However, the ident...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jha, Bhavya, Kumar, Deepak, Sharma, Arun, Dwivedy, Abhisek, Singh, Ramandeep, Biswal, Bichitra Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028948/
https://ncbi.nlm.nih.gov/pubmed/29752410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002299
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