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De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation

Intracellular pathogens including Mycobacterium tuberculosis (Mtb) have evolved with strategies to uptake amino acids from host cells to fulfil their metabolic requirements. However, Mtb also possesses de novo biosynthesis pathways for all the amino acids. This raises a pertinent question- how does...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Dwivedy, Abhisek, Ashraf, Anam, Jha, Bhavya, Kumar, Deepak, Agarwal, Nisheeth, Biswal, Bichitra K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994828/
https://ncbi.nlm.nih.gov/pubmed/33767335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01926-4
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