Učitavanje...

Lys66 residue as a determinant of high mismatch extension and misinsertion rates of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT)

A major factor contributing to the high mutation rate of HIV-1 RT is its high propensity for misincorporation. Misincorporation requires both dNTP misinsertion and the subsequent extension of the mismatched terminus thus formed. We hypothesized that Lys66 is a determinant of mismatch extension based...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Lwatula, Chisanga, Garforth, Scott J., Prasad, Vinayaka R.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472125/
https://ncbi.nlm.nih.gov/pubmed/22925131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08807.x
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!