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Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase
Human and mouse telomerases show a high degree of similarity in both the protein and RNA components. Human telomerase is more active and more processive than the mouse telomerase. There are two key differences between hTR [human TR (telomerase RNA)] and mTR (mouse TR) structures. First, the mouse te...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1533308/ https://ncbi.nlm.nih.gov/pubmed/16669789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060456 |
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