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Utilization of a Deoxynucleoside Diphosphate Substrate by HIV Reverse Transcriptase
BACKGROUND: Deoxynucleoside triphosphates (dNTPs) are the normal substrates for DNA synthesis catalyzed by polymerases such as HIV-1 reverse transcriptase (RT). However, substantial amounts of deoxynucleoside diphosphates (dNDPs) are also present in the cell. Use of dNDPs in HIV-1 DNA synthesis coul...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2312326/ https://ncbi.nlm.nih.gov/pubmed/18446195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002074 |
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