Panoramic view of a superfamily of phosphatases through substrate profiling

Large-scale activity profiling of enzyme superfamilies provides information about cellular functions as well as the intrinsic binding capabilities of conserved folds. Herein, the functional space of the ubiquitous haloalkanoate dehalogenase superfamily (HADSF) was revealed by screening a customized...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Huang, Hua, Pandya, Chetanya, Liu, Chunliang, Al-Obaidi, Nawar F., Wang, Min, Zheng, Li, Toews Keating, Sarah, Aono, Miyuki, Love, James D., Evans, Brandon, Seidel, Ronald D., Hillerich, Brandan S., Garforth, Scott J., Almo, Steven C., Mariano, Patrick S., Dunaway-Mariano, Debra, Allen, Karen N., Farelli, Jeremiah D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
PNAS Plus
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413258/
https://ncbi.nlm.nih.gov/pubmed/25848029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423570112
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