Panoramic view of a superfamily of phosphatases through substrate profiling

Large-scale activity profiling of enzyme superfamilies provides information about cellular functions as well as the intrinsic binding capabilities of conserved folds. Herein, the functional space of the ubiquitous haloalkanoate dehalogenase superfamily (HADSF) was revealed by screening a customized...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Huang, Hua, Pandya, Chetanya, Liu, Chunliang, Al-Obaidi, Nawar F., Wang, Min, Zheng, Li, Toews Keating, Sarah, Aono, Miyuki, Love, James D., Evans, Brandon, Seidel, Ronald D., Hillerich, Brandan S., Garforth, Scott J., Almo, Steven C., Mariano, Patrick S., Dunaway-Mariano, Debra, Allen, Karen N., Farelli, Jeremiah D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413258/
https://ncbi.nlm.nih.gov/pubmed/25848029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423570112
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