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An Anaerobic-Type α-Ketoglutarate Ferredoxin Oxidoreductase Completes the Oxidative Tricarboxylic Acid Cycle of Mycobacterium tuberculosis

Aerobic organisms have a tricarboxylic acid (TCA) cycle that is functionally distinct from those found in anaerobic organisms. Previous reports indicate that the aerobic pathogen Mycobacterium tuberculosis lacks detectable α-ketoglutarate (KG) dehydrogenase activity and drives a variant TCA cycle in...

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Hlavní autoři: Baughn, Anthony D., Garforth, Scott J., Vilchèze, Catherine, Jacobs, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773412/
https://ncbi.nlm.nih.gov/pubmed/19936047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000662
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