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Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities

Isoniazid (INH) is the cornerstone of tuberculosis (TB) chemotherapy, used for both treatment and prophylaxis of TB. The antimycobacterial activity of INH was discovered in 1952, and almost as soon as its activity was published, the first INH-resistant Mycobacterium tuberculosis strains were reporte...

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Detaylı Bibliyografya
Yayımlandı:Microbiol Spectr
Asıl Yazarlar: VILCHÈZE, CATHERINE, JACOBS, WILLIAM R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636829/
https://ncbi.nlm.nih.gov/pubmed/26104204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/microbiolspec.MGM2-0014-2013
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