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Characterization of Large Deletion Mutants of Mycobacterium tuberculosis Selected for Isoniazid Resistance

Large genomic deletions (LGDs) (6 to 63 kbp) were observed in isoniazid-resistant Mycobacterium tuberculosis mutants derived from four M. tuberculosis strains. These LGDs had no growth defect in vitro but could be defective in intracellular growth and showed various sensitivities toward oxidative st...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Antimicrob Agents Chemother
Κύριοι συγγραφείς: Vilchèze, Catherine, Saranathan, Rajagopalan, Weinrick, Brian, Jacobs, William R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449219/
https://ncbi.nlm.nih.gov/pubmed/32631825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00792-20
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