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Characterization of Large Deletion Mutants of Mycobacterium tuberculosis Selected for Isoniazid Resistance
Large genomic deletions (LGDs) (6 to 63 kbp) were observed in isoniazid-resistant Mycobacterium tuberculosis mutants derived from four M. tuberculosis strains. These LGDs had no growth defect in vitro but could be defective in intracellular growth and showed various sensitivities toward oxidative st...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7449219/ https://ncbi.nlm.nih.gov/pubmed/32631825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00792-20 |
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