Potent and selective effect of the mir-10b inhibitor MN-anti-mir10b in human cancer cells of diverse primary disease origin

por Yoo, Byunghee, Greninger, Patricia, Stein, Giovanna T., Egan, Regina K., McClanaghan, Joseph, Moore, Anna, Benes, Cyril H., Medarova, Zdravka
Publicado en PLoS One (2018)

Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors

por Sambrooks, Cecilia Lopez, Baro, Marta, Quijano, Amanda, Narayan, Azeet, Cui, Wei, Greninger, Patricia, Egan, Regina, Patel, Abhijit, Benes, Cyril H., Saltzman, W. Mark, Contessa, Joseph N.
Publicado en Cancer Res (2018)

BRAF and AXL oncogenes drive RIPK3 expression loss in cancer

por Najafov, Ayaz, Zervantonakis, Ioannis K., Mookhtiar, Adnan K., Greninger, Patricia, March, Ryan J., Egan, Regina K., Luu, Hoang Son, Stover, Daniel G., Matulonis, Ursula A., Benes, Cyril H., Yuan, Junying
Publicado en PLoS Biol (2018)

Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma

por Dalton, Krista M., Lochmann, Timothy L., Floros, Konstantinos V., Calbert, Marissa L., Kurupi, Richard, Stein, Giovanna T., McClanaghan, Joseph, Murchie, Ellen, Egan, Regina K., Greninger, Patricia, Dozmorov, Mikhail, Ramamoorthy, Sivapriya, Puchalapalli, Madhavi, Hu, Bin, Shock, Lisa, Koblinski, Jennifer, Glod, John, Boikos, Sosipatros A., Benes, Cyril H., Faber, Anthony C.
Publicado en Proc Natl Acad Sci U S A (2021)

Differential effector engagement by oncogenic KRAS

por Yuan, Tina L., Amzallag, Arnaud, Bagni, Rachel, Yi, Ming, Afghani, Shervin, Burgan, William, Fer, Nicole, Garvey, Leslie, Powell, Katie, Smith, Brian, Waters, Andrew M., Drubin, David, Thomson, Ty, Liao, Rosy, Greninger, Patricia, Stein, Giovanna T., Murchie, Ellen, Cortez, Eliane, Egan, Regina K., Procter, Lauren, Bess, Matthew, Cheng, Kwong Tai, Lee, Chih-Shia, Lee, Liam Changwoo, Fellmann, Christof, Stephens, Robert, Luo, Ji, Lowe, Scott, Benes, Cyril H., McCormick, Frank
Publicado en Cell Rep (2018)

Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC-dependence in intrahepatic cholangiocarcinoma

por Saha, Supriya K., Gordan, John D., Kleinstiver, Benjamin P., Vu, Phuong, Najem, Mortada S., Yeo, Jia-Chi, Shi, Lei, Kato, Yasutaka, Levin, Rebecca S., Webber, James T., Damon, Leah J., Egan, Regina K., Greninger, Patricia, McDermott, Ultan, Garnett, Mathew J., Jenkins, Roger L., Rieger-Christ, Kimberly M., Sullivan, Travis B., Hezel, Aram F., Liss, Andrew S., Mizukami, Yusuke, Goyal, Lipika, Ferrone, Cristina R., Zhu, Andrew X., Joung, J. Keith, Shokat, Kevan M., Benes, Cyril H., Bardeesy, Nabeel
Publicado en Cancer Discov (2016)

Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

por Sahu, Avinash Das, S Lee, Joo, Wang, Zhiyong, Zhang, Gao, Iglesias‐Bartolome, Ramiro, Tian, Tian, Wei, Zhi, Miao, Benchun, Nair, Nishanth Ulhas, Ponomarova, Olga, Friedman, Adam A, Amzallag, Arnaud, Moll, Tabea, Kasumova, Gyulnara, Greninger, Patricia, Egan, Regina K, Damon, Leah J, Frederick, Dennie T, Jerby‐Arnon, Livnat, Wagner, Allon, Cheng, Kuoyuan, Park, Seung Gu, Robinson, Welles, Gardner, Kevin, Boland, Genevieve, Hannenhalli, Sridhar, Herlyn, Meenhard, Benes, Cyril, Flaherty, Keith, Luo, Ji, Gutkind, J Silvio, Ruppin, Eytan
Publicado en Mol Syst Biol (2019)

A Landscape of Pharmacogenomic Interactions in Cancer

por Iorio, Francesco, Knijnenburg, Theo A., Vis, Daniel J., Bignell, Graham R., Menden, Michael P., Schubert, Michael, Aben, Nanne, Gonçalves, Emanuel, Barthorpe, Syd, Lightfoot, Howard, Cokelaer, Thomas, Greninger, Patricia, van Dyk, Ewald, Chang, Han, de Silva, Heshani, Heyn, Holger, Deng, Xianming, Egan, Regina K., Liu, Qingsong, Mironenko, Tatiana, Mitropoulos, Xeni, Richardson, Laura, Wang, Jinhua, Zhang, Tinghu, Moran, Sebastian, Sayols, Sergi, Soleimani, Maryam, Tamborero, David, Lopez-Bigas, Nuria, Ross-Macdonald, Petra, Esteller, Manel, Gray, Nathanael S., Haber, Daniel A., Stratton, Michael R., Benes, Cyril H., Wessels, Lodewyk F.A., Saez-Rodriguez, Julio, McDermott, Ultan, Garnett, Mathew J.
Publicado en Cell (2016)