Functionalizing genomic data for personalization of medicine

by Benes, Cyril H.
Published 2012

Direct pharmacological assessment of clinically acquired models as a strategy to overcome resistance to tyrosine kinase inhibitors

by Benes, Cyril H
Published in Mol Cell Oncol (2015)

Integrating complex genomic datasets and tumour cell sensitivity profiles to address a 'simple' question: which patients should get this drug?

by Benes, Cyril, Settleman, Jeff
Published 2009

EMT Twists the road to PI3Kinase

by Niederst, Matthew J., Benes, Cyril H.
Published 2014

TP53 mutation status: emerging biomarker for precision radiation medicine?

by Willers, Henning, Wang, Meng, Benes, Cyril H.
Published in Oncoscience (2018)

Statistical assessment and visualization of synergies for large-scale sparse drug combination datasets

by Amzallag, Arnaud, Ramaswamy, Sridhar, Benes, Cyril H.
Published in BMC Bioinformatics (2019)

P2X(7) Receptor Antagonists Display Agonist-like Effects on Cell Signaling Proteins

by Hedden, Lee, Benes, Cyril H., Soltoff, Stephen P.
Published 2011

Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation

by Manning, Amity L., Benes, Cyril, Dyson, Nicholas J.
Published 2013

APOBEC3A and 3B Activities Render Cancer Cells Susceptible to ATR Inhibition

by Buisson, Rémi, Lawrence, Michael S., Benes, Cyril H., Zou, Lee
Published in Cancer Res (2017)

Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase

by Buisson, Rémi, Boisvert, Jessica L., Benes, Cyril H., Zou, Lee
Published in Mol Cell (2015)

BIOM-60. BIOMARKER EVALUATION FOR IMIPRIDONE ONC206 REVEALS ClpP, ATF4, MYC, EGFR and HIF1 AS KEY PREDICTORS OF ANTI-CANCER EFFICACY

by Morrow, Sara, Garnett, Mathew, McDermott, Ultan, Benes, Cyril, Allen, Joshua, Prabhu, Varun
Published in Neuro Oncol (2020)

Differential determinants of cancer cell insensitivity to anti-mitotic drugs discriminated by a one-step cell imaging assay

by Tang, Yangzhong, Xie, Tiao, Florian, Stefan, Moerke, Nathan, Shamu, Caroline, Benes, Cyril, Mitchison, Timothy J.
Published 2013

Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features

by Buisson, Rémi, Langenbucher, Adam, Bowen, Danae, Kwan, Eugene E., Benes, Cyril H., Zou, Lee, Lawrence, Michael S.
Published in Science (2019)

Detection of Dysregulated Protein Association Networks by High-Throughput Proteomics Predicts Cancer Vulnerabilities

by Lapek, John D., Greninger, Patricia, Morris, Robert, Amzallag, Arnaud, Pruteanu-Malinici, Iulian, Benes, Cyril H., Haas, Wilhelm
Published in Nat Biotechnol (2017)

TAK1 (MAP3K7) inhibition promotes apoptosis in KRAS-dependent colon cancers

by Singh, Anurag, Sweeney, Michael F., Yu, Min, Burger, Alexa, Greninger, Patricia, Benes, Cyril, Haber, Daniel A., Settleman, Jeff
Published 2012

Toll-like Receptor (TLR) 2 Mediates Inflammatory Responses to Oligomerized RrgA Pneumococcal Pilus Type 1 Protein

by Basset, Alan, Zhang, Fan, Benes, Cyril, Sayeed, Sabina, Herd, Muriel, Thompson, Claudette, Golenbock, Douglas T., Camilli, Andrew, Malley, Richard
Published 2013

Machine Learning Prediction of Cancer Cell Sensitivity to Drugs Based on Genomic and Chemical Properties

by Menden, Michael P., Iorio, Francesco, Garnett, Mathew, McDermott, Ultan, Benes, Cyril H., Ballester, Pedro J., Saez-Rodriguez, Julio
Published 2013

CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers

by Heilmann, Andreas M., Perera, Rushika M., Ecker, Veronika, Nicolay, Brandon N., Bardeesy, Nabeel, Benes, Cyril H., Dyson, Nicholas J.
Published 2014

Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets

by Duan, Qiaonan, Wang, Zichen, Fernandez, Nicolas F., Rouillard, Andrew D., Tan, Christopher M., Benes, Cyril H., Ma’ayan, Avi
Published in Bioinformatics (2014)

Potent and selective effect of the mir-10b inhibitor MN-anti-mir10b in human cancer cells of diverse primary disease origin

by Yoo, Byunghee, Greninger, Patricia, Stein, Giovanna T., Egan, Regina K., McClanaghan, Joseph, Moore, Anna, Benes, Cyril H., Medarova, Zdravka
Published in PLoS One (2018)