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Passenger hotspot mutations in cancer driven by APOBEC3A and mesoscale genomic features
INTRODUCTION: Extensive tumor sequencing efforts have transformed the way in which cancer driver genes are identified. Appropriate statistical modeling is crucial for distinguishing true drivers from passenger events that accumulate during tumorigenesis but provide no fitness advantage to cancer cel...
Tallennettuna:
| Julkaisussa: | Science |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731024/ https://ncbi.nlm.nih.gov/pubmed/31249028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw2872 |
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