Potent and selective effect of the mir-10b inhibitor MN-anti-mir10b in human cancer cells of diverse primary disease origin

Since microRNAs (miRNAs, miRs) have been implicated in oncogenesis, many of them have been identified as therapeutic targets. Previously we have demonstrated that miRNA-10b acts as a master regulator of the viability of metastatic tumor cells and represents a target for therapeutic intervention. We...

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Publicat a:PLoS One
Autors principals: Yoo, Byunghee, Greninger, Patricia, Stein, Giovanna T., Egan, Regina K., McClanaghan, Joseph, Moore, Anna, Benes, Cyril H., Medarova, Zdravka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054402/
https://ncbi.nlm.nih.gov/pubmed/30028875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201046
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