Differential effector engagement by oncogenic KRAS

KRAS can bind numerous effector proteins, which activate different downstream signaling events. The best known are RAF, PI-3’ kinase and RalGDS families, but many additional direct and indirect effectors have been reported. We have assessed how these effectors contribute to several major phenotypes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Yuan, Tina L., Amzallag, Arnaud, Bagni, Rachel, Yi, Ming, Afghani, Shervin, Burgan, William, Fer, Nicole, Garvey, Leslie, Powell, Katie, Smith, Brian, Waters, Andrew M., Drubin, David, Thomson, Ty, Liao, Rosy, Greninger, Patricia, Stein, Giovanna T., Murchie, Ellen, Cortez, Eliane, Egan, Regina K., Procter, Lauren, Bess, Matthew, Cheng, Kwong Tai, Lee, Chih-Shia, Lee, Liam Changwoo, Fellmann, Christof, Stephens, Robert, Luo, Ji, Lowe, Scott, Benes, Cyril H., McCormick, Frank
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343826/
https://ncbi.nlm.nih.gov/pubmed/29444439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.051
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