Differential effector engagement by oncogenic KRAS

KRAS can bind numerous effector proteins, which activate different downstream signaling events. The best known are RAF, PI-3’ kinase and RalGDS families, but many additional direct and indirect effectors have been reported. We have assessed how these effectors contribute to several major phenotypes...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Yuan, Tina L., Amzallag, Arnaud, Bagni, Rachel, Yi, Ming, Afghani, Shervin, Burgan, William, Fer, Nicole, Garvey, Leslie, Powell, Katie, Smith, Brian, Waters, Andrew M., Drubin, David, Thomson, Ty, Liao, Rosy, Greninger, Patricia, Stein, Giovanna T., Murchie, Ellen, Cortez, Eliane, Egan, Regina K., Procter, Lauren, Bess, Matthew, Cheng, Kwong Tai, Lee, Chih-Shia, Lee, Liam Changwoo, Fellmann, Christof, Stephens, Robert, Luo, Ji, Lowe, Scott, Benes, Cyril H., McCormick, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343826/
https://ncbi.nlm.nih.gov/pubmed/29444439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.051
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