Development of siRNA payloads to target KRAS-mutant cancer

RNA interference (RNAi) is a powerful tool for target identification and can lead to novel therapies for pharmacologically intractable targets such as KRAS. RNAi therapy must combine potent siRNA payloads with reliable in vivo delivery for efficient target inhibition. We employed a functional “Senso...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yuan, Tina L., Fellmann, Christof, Lee, Chih-Shia, Ritchie, Cayde D., Thapar, Vishal, Lee, Liam C., Hsu, Dennis J., Grace, Danielle, Carver, Joseph O., Zuber, Johannes, Luo, Ji, McCormick, Frank, Lowe, Scott W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184972/
https://ncbi.nlm.nih.gov/pubmed/25100204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0900
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