EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells Against Ionizing Radiation

Therapeutics that target the epidermal growth factor receptor (EGFR) can enhance the cytotoxic effects of ionizing radiation (IR). However, predictive genomic biomarkers of this radiosensitization have remained elusive. By screening 40 non-small cell lung cancer cell (NSCLC) lines, we established a...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cancer Res
Hoofdauteurs: Wang, Meng, Kern, Ashley M., Hülskötter, Marieke, Greninger, Patricia, Singh, Anurag, Pan, Yunfeng, Chowdhury, Dipanjan, Krause, Mechthild, Baumann, Michael, Benes, Cyril H., Efstathiou, Jason A., Settleman, Jeff, Willers, Henning
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278592/
https://ncbi.nlm.nih.gov/pubmed/24648348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3157
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items