EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells Against Ionizing Radiation

Therapeutics that target the epidermal growth factor receptor (EGFR) can enhance the cytotoxic effects of ionizing radiation (IR). However, predictive genomic biomarkers of this radiosensitization have remained elusive. By screening 40 non-small cell lung cancer cell (NSCLC) lines, we established a...

詳細記述

保存先:
書誌詳細
出版年:Cancer Res
主要な著者: Wang, Meng, Kern, Ashley M., Hülskötter, Marieke, Greninger, Patricia, Singh, Anurag, Pan, Yunfeng, Chowdhury, Dipanjan, Krause, Mechthild, Baumann, Michael, Benes, Cyril H., Efstathiou, Jason A., Settleman, Jeff, Willers, Henning
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278592/
https://ncbi.nlm.nih.gov/pubmed/24648348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3157
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