Signaling Circuitries Controlling Stem Cell Fate: To Be or Not To Be

Yazar: Iglesias-Bartolome, Ramiro, Gutkind, J. Silvio
Baskı/Yayın Bilgisi 2011

Exploiting the mTOR paradox for disease prevention

Yazar: Iglesias-Bartolome, Ramiro, Gutkind, J. Silvio
Baskı/Yayın Bilgisi 2012

Exploiting the head and neck cancer oncogenome: Widespread PI3K-mTOR pathway alterations and novel molecular targets

Yazar: Iglesias-Bartolome, Ramiro, Martin, Daniel, Gutkind, J. Silvio
Yayımlandı Cancer Discov (2013)

Activation of GPCR-Gαi signaling increases keratinocyte proliferation and reduces differentiation, leading to epidermal hyperplasia

Yazar: Pedro, M. Pilar, Parra, Natalia Salinas, Gutkind, J. Silvio, Iglesias-Bartolome, Ramiro
Yayımlandı J Invest Dermatol (2019)

Protein kinase A inhibitor proteins (PKIs) divert GPCR-Gαs-cAMP signaling towards EPAC and ERK activation and are involved in tumor growth

Yazar: Hoy, James J., Parra, Natalia Salinas, Park, Jeannie, Kuhn, Skyler, Iglesias-Bartolome, Ramiro
Yayımlandı FASEB J (2020)

Targeted Delivery of Immunotoxin by Antibody to Ganglioside GD3: A Novel Drug Delivery Route for Tumor Cells

Yazar: Torres Demichelis, Vanina, Vilcaes, Aldo A., Iglesias-Bartolomé, Ramiro, Ruggiero, Fernando M., Daniotti, Jose L.
Baskı/Yayın Bilgisi 2013

YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity

Yazar: Yuan, Yao, Park, Jeannie, Feng, Amber, Awasthi, Parirokh, Wang, Zhiyong, Chen, Qianming, Iglesias-Bartolome, Ramiro
Yayımlandı Nat Commun (2020)

Insights into epithelial cell senescence from transcriptome and secretome analysis of human oral keratinocytes

Yazar: Schwartz, Rachael E., Shokhirev, Maxim N., Andrade, Leonardo R., Gutkind, J. Silvio, Iglesias-Bartolome, Ramiro, Shadel, Gerald S.
Yayımlandı Aging (Albany NY) (2021)

mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis

Yazar: Iglesias-Bartolome, Ramiro, Patel, Vyomesh, Cotrim, Ana, Leelahavanichkul, Kantima, Molinolo, Alfredo A., Mitchell, James B., Gutkind, J. Silvio
Baskı/Yayın Bilgisi 2012

Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands

Yazar: Zhu, Zhao, Pang, Baoxing, Iglesias-Bartolome, Ramiro, Wu, Xiaoshan, Hu, Lei, Zhang, Chunmei, Wang, Jinsong, Silvio Gutkind, J, Wang, Songlin
Yayımlandı Oncotarget (2016)

Combining Portable Raman Probes with Nanotubes for Theranostic Applications

Yazar: Bhirde, Ashwinkumar A., Liu, Gang, Jin, Albert, Iglesias-Bartolome, Ramiro, Sousa, Alioscka A., Leapman, Richard D., Gutkind, J. Silvio, Lee, Seulki, Chen, Xiaoyuan
Baskı/Yayın Bilgisi 2011

mTOR Co-Targeting in Cetuximab Resistance in Head and Neck Cancers Harboring PIK3CA and RAS Mutations

Yazar: Wang, Zhiyong, Martin, Daniel, Molinolo, Alfredo A., Patel, Vyomesh, Iglesias-Bartolome, Ramiro, Sol Degese, Maria, Vitale-Cross, Lynn, Chen, Qianming, Gutkind, J. Silvio
Baskı/Yayın Bilgisi 2014

mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model

Yazar: Callejas-Valera, Juan Luis, Iglesias-Bartolome, Ramiro, Amornphimoltham, Panomwat, Palacios-Garcia, Julia, Martin, Daniel, Califano, Joseph A., Molinolo, Alfredo A., Gutkind, J.Silvio
Yayımlandı Carcinogenesis (2016)

Inactivation of a Gαs-PKA tumor suppressor pathway in skin stem cells initiates basal-cell carcinogenesis

Yazar: Iglesias-Bartolome, Ramiro, Torres, Daniela, Marone, Romina, Feng, Xiaodong, Martin, Daniel, Simaan, May, Chen, Min, Weinstein, Lee S., Taylor, Susan S., Molinolo, Alfredo A., Gutkind, J. Silvio
Yayımlandı Nat Cell Biol (2015)

Nuclear Mapping of Nano-Drug Delivery Systems in Dynamic Cellular Environments

Yazar: Bhirde, Ashwinkumar A., Kapoor, Ankur, Liu, Gang, Iglesias-Bartolome, Ramiro, Jin, Albert, Zhang, Guofeng, Xing, Ruijun, Lee, Seulki, Leapman, Richard D., Gutkind, J Silvio, Chen, Xiaoyuan
Baskı/Yayın Bilgisi 2012

A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing GPCR-initiated mitogenic signals

Yazar: Vaqué, Jose P., Dorsam, Robert T., Feng, Xiaodong, Iglesias-Bartolome, Ramiro, Forsthoefel, David J., Chen, Qianming, Debant, Anne, Seeger, Mark A., Ksander, Bruce R., Teramoto, Hidemi, Gutkind, J. Silvio
Baskı/Yayın Bilgisi 2012

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA(+) oral cancers

Yazar: Yamaguchi, Kosuke, Iglesias-Bartolomé, Ramiro, Wang, Zhiyong, Callejas-Valera, Juan Luis, Amornphimoltham, Panomwat, Molinolo, Alfredo A., Cohen, Ezra E., Califano, Joseph A., Lippman, Scott M., Luo, Ji, Gutkind, J. Silvio
Yayımlandı Oncotarget (2016)

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-regulated Rho GTPase Signaling Circuitry

Yazar: Feng, Xiaodong, Degese, Maria Sol, Iglesias-Bartolome, Ramiro, Vaque, Jose P., Molinolo, Alfredo A., Rodrigues, Murilo, Zaidi, M. Raza, Ksander, Bruce R., Merlino, Glenn, Sodhi, Akrit, Chen, Qianming, Gutkind, J. Silvio
Baskı/Yayın Bilgisi 2014

A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium

Yazar: McGinn, Jamie, Hallou, Adrien, Han, Seungmin, Krizic, Kata, Ulyanchenko, Svetlana, Iglesias-Bartolome, Ramiro, England, Frances J., Verstreken, Christophe, Chalut, Kevin J., Jensen, Kim B., Simons, Benjamin D., Alcolea, Maria P.
Yayımlandı Nat Cell Biol (2021)

Transcriptional signature primes human oral mucosa for rapid wound healing

Yazar: Iglesias-Bartolome, Ramiro, Uchiyama, Akihiko, Molinolo, Alfredo A., Abusleme, Loreto, Brooks, Stephen R., Callejas-Valera, Juan Luis, Edwards, Dean, Doci, Colleen, Asselin-Labat, Marie-Liesse, Onaitis, Mark W., Moutsopoulos, Niki, Gutkind, J. Silvio, Morasso, Maria I.
Yayımlandı Sci Transl Med (2018)