Signaling Circuitries Controlling Stem Cell Fate: To Be or Not To Be

Por Iglesias-Bartolome, Ramiro, Gutkind, J. Silvio
Publicado em 2011

Exploiting the mTOR paradox for disease prevention

Por Iglesias-Bartolome, Ramiro, Gutkind, J. Silvio
Publicado em 2012

Exploiting the head and neck cancer oncogenome: Widespread PI3K-mTOR pathway alterations and novel molecular targets

Por Iglesias-Bartolome, Ramiro, Martin, Daniel, Gutkind, J. Silvio
Publicado no Cancer Discov (2013)

Targeted Delivery of Immunotoxin by Antibody to Ganglioside GD3: A Novel Drug Delivery Route for Tumor Cells

Por Torres Demichelis, Vanina, Vilcaes, Aldo A., Iglesias-Bartolomé, Ramiro, Ruggiero, Fernando M., Daniotti, Jose L.
Publicado em 2013

mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis

Por Iglesias-Bartolome, Ramiro, Patel, Vyomesh, Cotrim, Ana, Leelahavanichkul, Kantima, Molinolo, Alfredo A., Mitchell, James B., Gutkind, J. Silvio
Publicado em 2012

Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands

Por Zhu, Zhao, Pang, Baoxing, Iglesias-Bartolome, Ramiro, Wu, Xiaoshan, Hu, Lei, Zhang, Chunmei, Wang, Jinsong, Silvio Gutkind, J, Wang, Songlin
Publicado no Oncotarget (2016)

Combining Portable Raman Probes with Nanotubes for Theranostic Applications

Por Bhirde, Ashwinkumar A., Liu, Gang, Jin, Albert, Iglesias-Bartolome, Ramiro, Sousa, Alioscka A., Leapman, Richard D., Gutkind, J. Silvio, Lee, Seulki, Chen, Xiaoyuan
Publicado em 2011

mTOR Co-Targeting in Cetuximab Resistance in Head and Neck Cancers Harboring PIK3CA and RAS Mutations

Por Wang, Zhiyong, Martin, Daniel, Molinolo, Alfredo A., Patel, Vyomesh, Iglesias-Bartolome, Ramiro, Sol Degese, Maria, Vitale-Cross, Lynn, Chen, Qianming, Gutkind, J. Silvio
Publicado em 2014

Inactivation of a Gαs-PKA tumor suppressor pathway in skin stem cells initiates basal-cell carcinogenesis

Por Iglesias-Bartolome, Ramiro, Torres, Daniela, Marone, Romina, Feng, Xiaodong, Martin, Daniel, Simaan, May, Chen, Min, Weinstein, Lee S., Taylor, Susan S., Molinolo, Alfredo A., Gutkind, J. Silvio
Publicado no Nat Cell Biol (2015)

Nuclear Mapping of Nano-Drug Delivery Systems in Dynamic Cellular Environments

Por Bhirde, Ashwinkumar A., Kapoor, Ankur, Liu, Gang, Iglesias-Bartolome, Ramiro, Jin, Albert, Zhang, Guofeng, Xing, Ruijun, Lee, Seulki, Leapman, Richard D., Gutkind, J Silvio, Chen, Xiaoyuan
Publicado em 2012

A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing GPCR-initiated mitogenic signals

Por Vaqué, Jose P., Dorsam, Robert T., Feng, Xiaodong, Iglesias-Bartolome, Ramiro, Forsthoefel, David J., Chen, Qianming, Debant, Anne, Seeger, Mark A., Ksander, Bruce R., Teramoto, Hidemi, Gutkind, J. Silvio
Publicado em 2012

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA(+) oral cancers

Por Yamaguchi, Kosuke, Iglesias-Bartolomé, Ramiro, Wang, Zhiyong, Callejas-Valera, Juan Luis, Amornphimoltham, Panomwat, Molinolo, Alfredo A., Cohen, Ezra E., Califano, Joseph A., Lippman, Scott M., Luo, Ji, Gutkind, J. Silvio
Publicado no Oncotarget (2016)

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-regulated Rho GTPase Signaling Circuitry

Por Feng, Xiaodong, Degese, Maria Sol, Iglesias-Bartolome, Ramiro, Vaque, Jose P., Molinolo, Alfredo A., Rodrigues, Murilo, Zaidi, M. Raza, Ksander, Bruce R., Merlino, Glenn, Sodhi, Akrit, Chen, Qianming, Gutkind, J. Silvio
Publicado em 2014

Expression of an active Gα(s) mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance

Por Zhao, Xuefeng, Deng, Peng, Iglesias-Bartolome, Ramiro, Amornphimoltham, Panomwat, Steffen, Dana J., Jin, Yunyun, Molinolo, Alfredo A., de Castro, Luis Fernandez, Ovejero, Diana, Yuan, Quan, Chen, Qianming, Han, Xianglong, Bai, Ding, Taylor, Susan S., Yang, Yingzi, Collins, Michael T., Gutkind, J. Silvio
Publicado no Proc Natl Acad Sci U S A (2018)

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

Por Martin, Daniel, Degese, Maria S., Vitale-Cross, Lynn, Iglesias-Bartolome, Ramiro, Valera, Juan Luis Callejas, Wang, Zhiyong, Feng, Xiaodong, Yeerna, Huwate, Vadmal, Vachan, Moroishi, Toshiro, Thorne, Rick F., Zaida, Moraima, Siegele, Bradford, Cheong, Sok C., Molinolo, Alfredo A., Samuels, Yardena, Tamayo, Pablo, Guan, Kun Liang, Lippman, Scott M., Lyons, J. Guy, Gutkind, J. Silvio
Publicado no Nat Commun (2018)