Targeted Delivery of Immunotoxin by Antibody to Ganglioside GD3: A Novel Drug Delivery Route for Tumor Cells

Gangliosides are sialic acid-containing glycolipids expressed on plasma membranes from nearly all vertebrate cells. The expression of ganglioside GD3, which plays essential roles in normal brain development, decreases in adults but is up regulated in neuroectodermal and epithelial derived cancers. R...

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Main Authors: Torres Demichelis, Vanina, Vilcaes, Aldo A., Iglesias-Bartolomé, Ramiro, Ruggiero, Fernando M., Daniotti, Jose L.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561269/
https://ncbi.nlm.nih.gov/pubmed/23383146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055304
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