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Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies
Antibodies play a crucial role in host defense and are indispensable research tools, diagnostics, and therapeutics. Antibody generation involves binding of genomically encoded germline antibodies followed by somatic hypermutation and in vivo selection to obtain antibodies with high affinity and sele...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5572838/ https://ncbi.nlm.nih.gov/pubmed/28813678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.050 |
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