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Ganglioside GD2 as a Therapeutic Target for Antibody-Mediated Therapy in Osteosarcoma

BACKGROUND: Survival outcomes for patients with osteosarcoma have remained stagnant over the past three decades. Targeting of ganglioside GD2, a glycosphingolipid on the cell surface of some tumors, with immunotherapy has resulted in improved outcomes for patients with neuroblastoma. The expression...

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Main Authors: Roth, Michael, Linkowski, Marissa, Tarim, John, Piperdi, Sajida, Sowers, Rebecca, Geller, David, Gill, Jonathan, Gorlick, Richard
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946333/
https://ncbi.nlm.nih.gov/pubmed/24166473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28461
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