Insulin-Like Growth Factor 1 Receptor and Response to Anti-IGF1R Antibody Therapy in Osteosarcoma

BACKGROUND: Survival outcomes for patients with osteosarcoma (OS) have remained stagnant over the past three decades. Insulin-like growth factor 1 receptor (IGF1R) is over-expressed in a number of malignancies, and anti-IGF1R antibodies have and are currently being studied in clinical trials. Unders...

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Detalhes bibliográficos
Main Authors: Cao, Yu, Roth, Michael, Piperdi, Sajida, Montoya, Kristofer, Sowers, Rebecca, Rao, Pulivarthi, Geller, David, Houghton, Peter, Kolb, E. Anders, Gill, Jonathan, Gorlick, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149550/
https://ncbi.nlm.nih.gov/pubmed/25170759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106249
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