Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

Osteosarcoma patient survival has remained stagnant for 30 years. Novel therapeutic approaches are needed to improve outcomes. We examined the expression of Programmed Death Ligand 1 (PD-L1) and defined the tumor immune microenvironment to assess the prognostic utility in osteosarcoma. PD-L1 express...

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Publicado no:Sci Rep
Main Authors: Koirala, Pratistha, Roth, Michael E., Gill, Jonathan, Piperdi, Sajida, Chinai, Jordan M., Geller, David S., Hoang, Bang H., Park, Amy, Fremed, Michael A., Zang, Xingxing, Gorlick, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960483/
https://ncbi.nlm.nih.gov/pubmed/27456063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30093
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