Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

Osteosarcoma patient survival has remained stagnant for 30 years. Novel therapeutic approaches are needed to improve outcomes. We examined the expression of Programmed Death Ligand 1 (PD-L1) and defined the tumor immune microenvironment to assess the prognostic utility in osteosarcoma. PD-L1 express...

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Опубликовано в: :Sci Rep
Главные авторы: Koirala, Pratistha, Roth, Michael E., Gill, Jonathan, Piperdi, Sajida, Chinai, Jordan M., Geller, David S., Hoang, Bang H., Park, Amy, Fremed, Michael A., Zang, Xingxing, Gorlick, Richard
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960483/
https://ncbi.nlm.nih.gov/pubmed/27456063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30093
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