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mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis

The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and chemical insults compromising the repopulating capacity of the epithelial stem cell compartment. This is frequently the case in cancer patients r...

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Bibliografische gegevens
Hoofdauteurs: Iglesias-Bartolome, Ramiro, Patel, Vyomesh, Cotrim, Ana, Leelahavanichkul, Kantima, Molinolo, Alfredo A., Mitchell, James B., Gutkind, J. Silvio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477550/
https://ncbi.nlm.nih.gov/pubmed/22958932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.06.007
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