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mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis
The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and chemical insults compromising the repopulating capacity of the epithelial stem cell compartment. This is frequently the case in cancer patients r...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477550/ https://ncbi.nlm.nih.gov/pubmed/22958932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.06.007 |
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