Loading...
Activation of GPCR-Gαi signaling increases keratinocyte proliferation and reduces differentiation, leading to epidermal hyperplasia
G-protein-coupled receptors (GPCRs) and their associated heterotrimeric G proteins impinge on pathways that control epithelial cell self-renewal and differentiation. While it is known that Gαs signaling regulates skin homeostasis in vivo, the role of GPCR-coupled Gαi proteins in the skin is unclear....
Saved in:
| Published in: | J Invest Dermatol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202966/ https://ncbi.nlm.nih.gov/pubmed/31707029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2019.10.012 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|