Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11

by Di Virgilio, Michela, Gautier, Jean
Published 2005

MAD2L2 Promotes Open Chromatin in Embryonic Stem Cells and Derepresses the Dppa3 Locus

by Rahjouei, Ali, Pirouz, Mehdi, Di Virgilio, Michela, Kamin, Dirk, Kessel, Michael
Published in Stem Cell Reports (2017)

53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function

by Sundaravinayagam, Devakumar, Rahjouei, Ali, Andreani, Matteo, Tupiņa, Dagnija, Balasubramanian, Sandhya, Saha, Tannishtha, Delgado-Benito, Verónica, Coralluzzo, Violeta, Daumke, Oliver, Di Virgilio, Michela
Published in Cell Rep (2019)

Essential role for DNA-PKcs in DNA double strand break repair and apoptosis in ATM deficient lymphocytes

by Callén, Elsa, Jankovic, Mila, Wong, Nancy, Zha, Shan, Chen, Hua-Tang, Difilippantonio, Simone, Di Virgilio, Michela, Heidkamp, Gordon, Alt, Frederick W., Nussenzweig, André, Nussenzweig, Michel
Published 2009

Amino-Terminal Phosphorylation of Activation-Induced Cytidine Deaminase Suppresses c-myc/IgH Translocation

by Gazumyan, Anna, Timachova, Ksenia, Yuen, Grace, Siden, Edward, Di Virgilio, Michela, Woo, Eileen M., Chait, Brian T., Reina San-Martin, Bernardo, Nussenzweig, Michel C., McBride, Kevin M.
Published 2011

Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes

by Klein, Isaac A., Resch, Wolfgang, Jankovic, Mila, Oliveira, Thiago, Yamane, Arito, Nakahashi, Hirotaka, Di Virgilio, Michela, Bothmer, Anne, Nussenzweig, Andre, Robbiani, Davide F., Casellas, Rafael, Nussenzweig, Michel C.
Published 2011

Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1

by Bothmer, Anne, Robbiani, Davide F., Di Virgilio, Michela, Bunting, Samuel F., Klein, Isaac A., Feldhahn, Niklas, Barlow, Jacqueline, Chen, Henry T., Bosque, David, Callen, Elsa, Nussenzweig, André, Nussenzweig, Michel C.
Published 2011

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

by Di Virgilio, Michela, Callen, Elsa, Yamane, Arito, Zhang, Wenzhu, Jankovic, Mila, Gitlin, Alexander D., Feldhahn, Niklas, Resch, Wolfgang, Oliveira, Thiago Y., Chait, Brian T., Nussenzweig, André, Casellas, Rafael, Robbiani, Davide F., Nussenzweig, Michel C.
Published 2013

MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh Translocation

by Dorsett, Yair, McBride, Kevin M., Jankovic, Mila, Gazumyan, Anna, Thai, To-Ha, Robbiani, Davide F., Di Virgilio, Michela, San-Martin, Bernardo Reina, Heidkamp, Gordon, Schwickert, Tanja A., Eisenreich, Thomas, Rajewsky, Klaus, Nussenzweig, Michel C.
Published 2008

Activation Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5

by Pavri, Rushad, Gazumyan, Anna, Jankovic, Mila, Di Virgilio, Michela, Klein, Isaac, Ansarah-Sobrinho, Camilo, Resch, Wolfgang, Yamane, Arito, San-Martin, Bernardo Reina, Barreto, Vasco, Nieland, Thomas J., Root, David E., Casellas, Rafael, Nussenzweig, Michel C.
Published 2010

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

by Delgado-Benito, Verónica, Berruezo-Llacuna, Maria, Altwasser, Robert, Winkler, Wiebke, Sundaravinayagam, Devakumar, Balasubramanian, Sandhya, Caganova, Marieta, Graf, Robin, Rahjouei, Ali, Henke, Marie-Thérèse, Driesner, Madlen, Keller, Lisa, Prigione, Alessandro, Janz, Martin, Akalin, Altuna, Di Virgilio, Michela
Published in J Exp Med (2020)

An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex

by Kracker, Sven, Di Virgilio, Michela, Schwartzentruber, Jeremy, Cuenin, Cyrille, Forveille, Monique, Deau, Marie-Céline, McBride, Kevin M., Majewski, Jacek, Gazumyan, Anna, Seneviratne, Suranjith, Grimbacher, Bodo, Kutukculer, Necil, Herceg, Zdenko, Cavazzana, Marina, Jabado, Nada, Nussenzweig, Michel C., Fischer, Alain, Durandy, Anne
Published in J Allergy Clin Immunol (2015)

The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination

by Delgado-Benito, Verónica, Rosen, Daniel B., Wang, Qiao, Gazumyan, Anna, Pai, Joy A., Oliveira, Thiago Y., Sundaravinayagam, Devakumar, Zhang, Wenzhu, Andreani, Matteo, Keller, Lisa, Kieffer-Kwon, Kyong-Rim, Pękowska, Aleksandra, Jung, Seolkyoung, Driesner, Madlen, Subbotin, Roman I., Casellas, Rafael, Chait, Brian T., Nussenzweig, Michel C., Di Virgilio, Michela
Published in Mol Cell (2018)

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions

by Callen, Elsa, Di Virgilio, Michela, Kruhlak, Michael J., Nieto-Soler, Maria, Wong, Nancy, Chen, Hua-Tang, Faryabi, Robert B., Polato, Federica, Santos, Margarida, Starnes, Linda M., Wesemann, Duane R., Lee, Ji-Eun, Tubbs, Anthony, Sleckman, Barry P., Daniel, Jeremy A., Ge, Kai, Alt, Frederick W., Fernandez-Capetillo, Oscar, Nussenzweig, Michel C., Nussenzweig, André
Published 2013

DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency

by Volk, Timo, Pannicke, Ulrich, Reisli, Ismail, Bulashevska, Alla, Ritter, Julia, Björkman, Andrea, Schäffer, Alejandro A., Fliegauf, Manfred, Sayar, Esra H., Salzer, Ulrich, Fisch, Paul, Pfeifer, Dietmar, Di Virgilio, Michela, Cao, Hongzhi, Yang, Fang, Zimmermann, Karin, Keles, Sevgi, Caliskaner, Zafer, Güner, S¸ükrü, Schindler, Detlev, Hammarström, Lennart, Rizzi, Marta, Hummel, Michael, Pan-Hammarström, Qiang, Schwarz, Klaus, Grimbacher, Bodo
Published in Hum Mol Genet (2015)

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

by Inak, Gizem, Rybak-Wolf, Agnieszka, Lisowski, Pawel, Pentimalli, Tancredi M., Jüttner, René, Glažar, Petar, Uppal, Karan, Bottani, Emanuela, Brunetti, Dario, Secker, Christopher, Zink, Annika, Meierhofer, David, Henke, Marie-Thérèse, Dey, Monishita, Ciptasari, Ummi, Mlody, Barbara, Hahn, Tobias, Berruezo-Llacuna, Maria, Karaiskos, Nikos, Di Virgilio, Michela, Mayr, Johannes A., Wortmann, Saskia B., Priller, Josef, Gotthardt, Michael, Jones, Dean P., Mayatepek, Ertan, Stenzel, Werner, Diecke, Sebastian, Kühn, Ralf, Wanker, Erich E., Rajewsky, Nikolaus, Schuelke, Markus, Prigione, Alessandro
Published in Nat Commun (2021)

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

by Boege, Yannick, Malehmir, Mohsen, Healy, Marc E., Bettermann, Kira, Lorentzen, Anna, Vucur, Mihael, Ahuja, Akshay K., Böhm, Friederike, Mertens, Joachim C., Shimizu, Yutaka, Frick, Lukas, Remouchamps, Caroline, Mutreja, Karun, Kähne, Thilo, Sundaravinayagam, Devakumar, Wolf, Monika J., Rehrauer, Hubert, Koppe, Christiane, Speicher, Tobias, Padrissa-Altés, Susagna, Maire, Renaud, Schattenberg, Jörn M., Jeong, Ju-Seong, Liu, Lei, Zwirner, Stefan, Boger, Regina, Hüser, Norbert, Davis, Roger J., Müllhaupt, Beat, Moch, Holger, Schulze-Bergkamen, Henning, Clavien, Pierre-Alain, Werner, Sabine, Borsig, Lubor, Luther, Sanjiv A., Jost, Philipp J., Weinlich, Ricardo, Unger, Kristian, Behrens, Axel, Hillert, Laura, Dillon, Christopher, Di Virgilio, Michela, Wallach, David, Dejardin, Emmanuel, Zender, Lars, Naumann, Michael, Walczak, Henning, Green, Douglas R., Lopes, Massimo, Lavrik, Inna, Luedde, Tom, Heikenwalder, Mathias, Weber, Achim
Published in Cancer Cell (2017)